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3 mentions found


☆ Researchers return to Alzheimer's vaccines, buoyed by recent drug success
  + stars: | 2023-11-20 | by ( Julie Steenhuysen | ) www.reuters.com   time to read: +6 min
The renewed interest in Alzheimer's vaccines follows a promising first attempt more than 20 years ago that was abandoned after 6% of study volunteers developed life-threatening brain inflammation known as meningoencephalitis. Dr. Reisa Sperling, an Alzheimer's researcher at Mass General Brigham in Boston, said she believes vaccines will play an important role as researchers look to prevent Alzheimer's. She is considering vaccines for her next study in asymptomatic people with Alzheimer's proteins in their blood, but not enough to register on brain scans. Alzheimer's vaccines are still in the early stages and will require large, years-long trials to show they work. Generating a strong immune response is critical for such vaccines, which would typically be given to older individuals with weaker immune systems, he said.
Persons: Brian Snyder, Eli Lilly's, Reisa Sperling, Brigham, “, ” Sperling, Walter Koroshetz, Mei Mei Hu, Vaxxinity, Hu, Michael Rafii, Rafii, Andrea Pfiefer, Johnson, Prothena, Gene Kinney, Julie Steenhuysen, Caroline Humer, Bill Berkrot Organizations: Alzheimer Research, Brigham, Women's, REUTERS, Rights, U.S . Food, Drug Administration, Mass, National Institutes of Health, UB, University of Southern, Johnson, Bristol Myers Squibb, Thomson Locations: Boston , Massachusetts, U.S, Boston, Taiwan, University of Southern California
☆ Is Buying Real Estate With a Friend Really a Good Idea?
  + stars: | 2023-10-31 | by ( Tim Mckeough | ) www.nytimes.com   time to read: 1 min
In the early days of the pandemic, Jonathan Travis and his friend Ethan Rafii were visiting another friend’s country house outside New York City when they began to dream big. What if they pooled their resources and bought a shared house together? “To be candid, we were having a mushroom experience,” said Mr. Rafii, 38, who works in finance and is a partner in Kettl, a Japanese tea company. He and Mr. Travis had become friends through a shared passion for art. As they were lounging that night, Mr. Travis suggested that a shared house could be not only a getaway from their Manhattan apartments, but a place to display their collections and maybe start an artists’ residency.
Persons: Jonathan Travis, Ethan Rafii, ”, Rafii, Travis Locations: New York City, Kettl, Manhattan
☆ Down syndrome families' fight for access to Alzheimer’s trials, treatments
  + stars: | 2023-10-10 | by ( Julie Steenhuysen | ) www.reuters.com   time to read: +9 min
In an extended portion of Eisai’s main Leqembi trial, CAA was associated with one death. 'THE DIGNITY OF RISK'Hillerstrom said the groups are "very strongly" lobbying Eisai and Lilly to conduct the safety trials in Down syndrome, and said he has been meeting with the companies to push them to design such trials. Lilly declined to comment on whether it is considering either a safety trial or taking part in that study. An Eisai spokeswoman said the company "has no immediate plans" to conduct clinical trials of Leqembi in people with Down syndrome. The company is collaborating with LuMind in a study gathering data on how Alzheimer's manifests in people with Down syndrome.
Persons: Oskar Hillerstrom, Lianor, Hampus, Brian Snyder, Lianor da Cunha, Oskar, de Oeiras, Teresa, Oskar’s, Hampus Hillerstrom, Eli Lilly's, LuMind, Hillerstrom, Lilly, Emily Largent, Beau Ances, Louis, I've, Ances, I'm, Michael Rafii, William Mobley, Mobley, Dawn Brooks, donanemab, Margot Rhondeau, Hannah, Julie Steenhuysen, Caroline Humer, Bill Berkrot Organizations: REUTERS, Rights, Reuters, CAA, University of Pennsylvania Perelman School of Medicine, Medicare, U.S . Food, Drug Administration, Washington University, National Institute, Aging, University of Southern, UC San Diego School of Medicine, LuMind, Syndrome, Thomson Locations: Lexington , Massachusetts, U.S, Santo, Portugal, United States, St, University of Southern California
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